= Abnormal increased erythrocyte dissolution:
- Shortened erythrocyte lifetime
- Compensatory enhanced erythropoiesis
- Increase in indirect bilirubin
- Haptaglobin in the serum
- Possibly also hemoglobinuria
= Word-finding disorder with preserved terminology and language understanding and in case of intact spontaneous erythrocyte eruption
= Very small blood vessels passing in capillary, which lead the blood from the heart to an organ or tissue.
= Cell layer on the inner surface of the blood and lymph vessels
= Red blood cell, which carries out the oxygen transport in the organism with its hemoglobin and performs active ATP-dependent metabolic performances
= concerning a disease
= Strong deformed erythrocyte, especially in intravascular hemolysis
= Injury or disturbance of the function of a vessel
= The red blood dye and its variants
= In the narrow sense, the normal HbA1 contained in the erythrocytes
= Occur free hemoglobin in the blood with severe hemolysis as a consequence of inadequate binding by the haptoglobin, possibly with hemoglobinurie
= Complete or incomplete paralysis of one half of the body
= Glassy-transparent protein mass converted from tissues
= Pathological exsanguination or poor blood circulation of a tissue due to insufficient or missing arterial blood supply
= Leads to oxygen deficiency, with fading, cooling and volume reduction of the affected tissues
= Changes of small and small arteries
Microangiopathy, thrombotic (TMA)
= Describes the vascular problem with TTP:
The vascular sections are completely occluded by thromboses formed from platelets and von Willebrand factor. They show a swelling and proliferation of the endothelium - but no inflammatory reaction. There are deposits of hygienic material that is not fibrin.
= Smallest, punctual skin or mucosal bleeding (capillary bleeding)
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= Protein-cleaving enzymes (= mostly proteins):
Proteases cleave the proteins as enzymes
= Blood platelets
= In two-phase clumping of thrombocytes in the course of the physiological bleeding, mediated by a glycoprotein complex of the membrane (envelope of the thrombocyte), but also in the pathological development of a thrombus
On contact with free collagen fibrils (e.g., injured vessel wall) and ADP or with immune complexes, thrombocyte aggregation is increased, clumps are formed which, however, can still disintegrate.
The platelet aggregates no longer disintegrate.
= A thrombus consists of several platelet aggregates and fibrin. It is always pathological.
= Large protein, which influences the interaction between platelets and the blood vessel walls. It is formed by the vessel endothelium and megakaryocytes.
= Protective protein for Factor VIII
= Transport protein for factor VIII in the blood
= Adhesive protein, which adheres to the adhesion of platelets to the site of injury